Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler. Keen questions Reddington's sudden interest in her, though he claims that Keen is very special. After the FBI brings down a terrorist he provided information on, Reddington reveals that the terrorist is only just the first of many. In the last two decades, he's made a list of criminals and terrorists he believes the FBI cannot find because they did not know they exist and that they matter the most. Reddington calls it "The Blacklist".
While continuing to battle Berlin, Red faces a new threat in the form of Lord Baltimore. A figure from Red's past returns. Liz tries to move on after her showdown with Tom.